http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#Head http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://www.nanopub.org/nschema#hasAssertion http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#assertion http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://www.nanopub.org/nschema#hasProvenance http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#provenance http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://www.nanopub.org/nschema#hasPublicationInfo http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#pubinfo http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#assertion http://purl.obolibrary.org/obo/DOID_8986 https://w3id.org/biolink/vocab/category https://w3id.org/biolink/vocab/Disease http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://purl.obolibrary.org/obo/DOID_8986 http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate https://w3id.org/biolink/vocab/treats http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://identifiers.org/drugbank:DB00745 http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association http://www.w3.org/2000/01/rdf-schema#label modafinil tablets are indicated to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy obstructive sleep apnea and shift work disorder in osa modafinil tablets are indicated as an adjunct to standard treatment s for the underlying obstruction if continuous positive airway pressure cpap is the treatment of choice for a patient a maximal effort to treat with cpap for an adequate period of time should be made prior to initiating modafinil tablets if modafinil tablets are used adjunctively with cpap the encouragement of and periodic assessment of cpap compliance is necessary in all cases careful attention to the diagnosis and treatment of the underlying sleep disorder s is of utmost importance prescribers should be aware that some patients may have more than one sleep disorder contributing to their excessive sleepiness the effectiveness of modafinil in long term use greater than 9 weeks in narcolepsy clinical trials and 12 weeks in osa and swd clinical trials has not been systematically evaluated in placebo controlled trials the physician who elects to prescribe modafinil tablets for an extended time in patients with narcolepsy osa or swd should periodically reevaluate long term usefulness for the individual patient http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association https://w3id.org/biolink/vocab/association_type https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association https://w3id.org/biolink/vocab/provided_by https://w3id.org/um/NeuroDKG http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#association https://w3id.org/biolink/vocab/relation https://w3id.org/um/neurodkg/SymptomaticReliefIndication https://identifiers.org/drugbank:DB00745 https://w3id.org/biolink/vocab/category https://w3id.org/biolink/vocab/Drug http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#provenance http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#assertion http://www.w3.org/ns/prov#wasAttributedTo https://orcid.org/0000-0002-1468-3557 http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#pubinfo http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#sig http://purl.org/nanopub/x/hasAlgorithm RSA http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#sig http://purl.org/nanopub/x/hasPublicKey MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#sig http://purl.org/nanopub/x/hasSignature XbqdWmXKWZNWBVKTWlyvZrRgqSYc3EJ5kjw/hyKDrp/YbboLFaJjngKXlGDNeks+AyUvlkNr3pdsgfZEweUsS7VBxfzzy0LJ/BuC8FtiSr9teXFQ+J084AiAjCSJiQKWSiVbEjZiE9XglyYNhtR4yAEGKZzY1+YJVkhTdsiOU74= http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs#sig http://purl.org/nanopub/x/hasSignatureTarget http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://purl.org/dc/terms/created 2021-06-15T17:56:26.387+02:00 http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs http://purl.org/dc/terms/creator https://orcid.org/0000-0002-1468-3557 http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM http://purl.org/np/RAFQ8Rl_r-QAiWZVJSBR1RrBiIlQPkqE20Kyw4FQK2DWs https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs