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Finally, simulations were performed to predict the antitumor efficacy of dexamethasone (DEX) combined with dopamine D(2)-like receptor (D2DR) antagonist sulpiride (SUL) under various dose regimens, where changing dosing frequency of dopamine D(2)-like receptor (D2DR) antagonist sulpiride (SUL) had little effect, while the antitumor efficacy of DEX combined with SUL was predicted to be improved when dexamethasone (DEX) was given more frequently.
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