. . . . . . . "[This approach classified CRC into two major groups consistent with previous classification systems: (1) ?16�% hypermutated cancers with either microsatellite instability (MSI) due to defective mismatch repair (?13�%) or ultramutated cancers with DNA polymerase epsilon proofreading mutations (?3�%); and (2) ?84�% non-hypermutated, microsatellite stable (MSS) cancers with a high frequency of DNA somatic copy number alterations, which showed common mutations in APC, TP53, KRAS, SMAD4, and PIK3CA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:22+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .