@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix this: <http://purl.org/np/RA5cECNwPPBB3Mr8HqA5JEYqs-HHYO00W_pJGPLfZeVmI> .
@prefix sub: <http://purl.org/np/RA5cECNwPPBB3Mr8HqA5JEYqs-HHYO00W_pJGPLfZeVmI#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:association rdf:object <http://www.ebi.ac.uk/efo/EFO_0009854>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/DRUGBANK:DB01221>;
    a rdf:Statement;
    rdfs:label "These findings suggest that if ketamine is to find a place as an off-label treatment for depression and suicidality in mainstream psychiatry, researchers should study the safety, efficacy, and optimization of oral ketamine. Intravenous and intranasal routes may be monetarily more promising, but the oral route could be of greatest service.";
    bl:has_population_context sub:context;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/30946543>;
    bl:relation nkg:OffLabelIndication .
  
  sub:context a bl:Cohort;
    rdfs:label "Adults" .
  
  <http://www.ebi.ac.uk/efo/EFO_0009854> a bl:Disease .
  
  <https://identifiers.org/DRUGBANK:DB01221> a bl:Drug .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2021-08-24T18:49:22.022386"^^xsd:dateTime .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "jpyDVynXyC3n6LUjv7e8w7F2iNFdepVg0mbM4LsfVKroNyuV9SUpRH91IFEFm4yvcDdLgvvQSbYld/wqPz+8CtgVfZ9KRkDZW9DBqEFjDNzCN4D7bnMuMcQGFK1CwpwajPiKOfb8ZgqG09Xb/45nCll+0BJ2WXZX3sxTB1WzdkQ=";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2021-08-24T18:49:22.022386"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-7641-6446;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}