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[In contrast, TCR-transgenic mice deprived of mHFE molecules (mHfe KO mice) or expressing a C282?Y mutated mHFE molecule - the most frequent mutation associated with human hereditary hemochromatosis - positively selected mHFE-reactive CD8(+) T lymphocytes and were not tolerant toward mHFE.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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