http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#Head
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://www.nanopub.org/nschema#hasAssertion
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#assertion
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://www.nanopub.org/nschema#hasProvenance
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#provenance
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://www.nanopub.org/nschema#hasPublicationInfo
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#pubinfo
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#assertion
http://purl.obolibrary.org/obo/DOID_409
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/Disease
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
http://purl.obolibrary.org/obo/DOID_409
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
https://w3id.org/biolink/vocab/treats
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
https://identifiers.org/drugbank:DB01076
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
http://www.w3.org/2000/01/rdf-schema#label
"Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels (4.1) Women who are pregnant or may become pregnant (4.3) Nursing mothers (4.4). Hypersensitivity to any component of this medication (4.2) Active liver disease which may include unexplained persistent elevations of hepatic transaminase levels Hypersensitivity to any component of this medication Women who are pregnant or may become pregnant. Atorvastatin calcium may cause fetal harm when administered to a pregnant woman. Serum cholesterol and triglycerides increase during normal pregnancy, and cholesterol or cholesterol derivatives are essential for fetal development. Atherosclerosis is a chronic process and discontinuation of lipid-lowering drugs during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. There are no adequate and well-controlled studies of atorvastatin calcium use during pregnancy; however in rare reports, congenital anomalies were observed following intrauterine exposure to statins. In rat and rabbit animal reproduction studies, atorvastatin revealed no evidence of teratogenicity. ATORVASTATIN CALCIUM SHOULD BE ADMINISTERED TO WOMEN OF CHILDBEARING AGE ONLY WHEN SUCH PATIENTS ARE HIGHLY UNLIKELY TO CONCEIVE AND HAVE BEEN INFORMED OF THE POTENTIAL HAZARDS. If the patient becomes pregnant while taking this drug, atorvastatin calcium should be discontinued immediately and the patient apprised of the potential hazard to the fetus [see Use in Specific Populations (8.1 ) It is not known whether atorvastatin is excreted into human milk; however a small amount of another drug in this class does pass into breast milk. Because statins have the potential for serious adverse reactions in nursing infants, women who require atorvastatin calcium treatment should not breastfeed their infants [see Use in Specific Populations (8.3)"
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
https://w3id.org/biolink/vocab/provided_by
https://w3id.org/um/NeuroDKG
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#association
https://w3id.org/biolink/vocab/relation
https://schema.org/MedicalContraindication
https://identifiers.org/drugbank:DB01076
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/Drug
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#provenance
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#assertion
http://www.w3.org/ns/prov#wasAttributedTo
https://orcid.org/0000-0002-1468-3557
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#pubinfo
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#sig
http://purl.org/nanopub/x/hasAlgorithm
RSA
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#sig
http://purl.org/nanopub/x/hasPublicKey
MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#sig
http://purl.org/nanopub/x/hasSignature
Cx2FJdj/gWk/UB5FCBEERnZgGCC98kgX+6VQTpxS3ZTSAFIhN0CA2nzOF5gU75XcDd6R1+OWK6P0ZkC3eLcqk3VeKWto+mypX5rMkyK1PUqr4C9KeuaFGH/OzzyAFs9ODNkD1NBX6XkTzAiJ7qc/oNjkXPX+KfKGXxhydoJGaBw=
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec#sig
http://purl.org/nanopub/x/hasSignatureTarget
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://purl.org/dc/terms/created
2021-08-23T12:06:13.772+02:00
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
http://purl.org/dc/terms/creator
https://orcid.org/0000-0002-1468-3557
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
http://purl.org/np/RA3HAU7gjqWwHnuixmjacloazylNNDAEDxjsx1JmtUSec
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY