@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix ns1: <
https://w3id.org/np/o/ntemplate/
> .
@prefix this: <
http://purl.org/np/RA2DM6QaBO5ODu0ugC6WyedLtBObXkGfNFb4aiMUJz11k
> .
@prefix sub: <
http://purl.org/np/RA2DM6QaBO5ODu0ugC6WyedLtBObXkGfNFb4aiMUJz11k#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_8545
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/DOID_8545
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://identifiers.org/drugbank:DB01189
> ;
a
rdf:Statement
;
rdfs:label
"\"The use of Desflurane, USP, Liquid for Inhalation is contraindicated in the following conditions: Known or suspected genetic susceptibility to malignant hyperthermia. Patients in whom general anesthesia is contraindicated. Induction of anesthesia in pediatric patients. Patients with known sensitivity to Desflurane, USP, Liquid for Inhalation or to other halogenated agents [See Warnings and Precautions (5.6) ] Patients with a history of moderate to severe hepatic dysfunction following anesthesia with Desflurane, USP, Liquid for Inhalation or other halogenated agents and not otherwise explained [See Warnings and Precautions (5.6) ] Patients with known or suspected genetic susceptibility to malignant hyperthermia ( 4 Patients in whom general anesthesia is contraindicated ( 4 Induction of anesthesia in pediatric patients ( 4 Patients with known sensitivity to halogenated agents ( 4 Patients with a history of moderate to severe hepatic dysfunction following anesthesia with halogenated agents and not otherwise explained. ( 4\"" ;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:relation
schema:MedicalContraindication
.
<
https://identifiers.org/drugbank:DB01189
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"Iz9yA6DdIj+PBHkDsl+AItIAtbOGFjhUPTDs8ak1b2VyoXJlo0uwgLes/Vf9tJucg8Y15ilLEEInmHEAXB6N7icq0byw7k+hCI7UjC6GS+ZZimpbnD08ixSCLxWQbBqYZ4nA4Hxyfdphpv7dKkGmFhNZWQDMGTiaz1i5JsWse9M=" ;
npx:hasSignatureTarget
this:
.
this:
dct:created
"2021-08-23T18:52:49.113+02:00"^^
xsd:dateTime
;
dct:creator
orcid:0000-0002-1468-3557
;
ns1:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
ns1:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
ns1:wasCreatedFromTemplate
<
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
> .
}