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[Because expression of sorLA is reduced in the brain of patients with Alzheimer's disease (AD), we tested involvement of this receptor in intracellular transport and processing of the amyloid precursor protein (APP) to the amyloid beta-peptide (Abeta), the principal component of senile plaques.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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